Issued Patents

• 2025

  Inventors	Patent No.	Issue Date	Title
  Iwao Ojima	12,186,428	1/7/2025	Combination Taxoid Nanoemulsion with Immunotherapy in Cancer
  Scott Laughlin, Pratik Kumar, Ting Jiang, Wei Huang	12,194,023	1/14/2025	Compositions and Methods for Modular Coltrol of Bioorthogonal Ligation
  Arthur P. Grollman, Kathleen Dickman	12,195,803	1/14/2025	Methods and Materials for Assessing and Treating Cancer
  Andrew LaBella, Amirhossein Goldan, Wei Zhao, Eric Petersen	12,213,820	2/4/2025	High Resolution and High Sensitivity PET Scanner with PET Detector Modules
  Michael Dapolito, Mengkun Liu, Xinzhong Chen	12,247,998	3/11/2025	Scattering-type Scanning Near-field Optical Microscopy with Akiyama Piezo-probes
  Gerald Smaldone	12,251,510	3/18/2025	Breath-Enhanced Nebulizer for Delivery of Aerosolized Drugs to Ventilated Patients
  Matthew Eisaman, Jan Folkson, Joseph Andrade	12,262,520	3/25/2025	Graphene Laminate Structures
  Amirhossein Goldan, Andrew Labella, Wei Zhao, Anthony R. Lubinsky	12,265,190	4/1/2025	High Resolution Depth-encoding PET Detector with Prismatoid Light Guide Array
  Joel Haskin Saltz, Tahsin M. Kurc, Yi Gao, Wei Zhu, Si Wen, Tianhao Zhao, Sampurna Shrestha	12,272,059	4/8/2025	System and Method Associated with Predicting Segmentation Quality of Objects in Analysis of Copious Image Data
  Alexander Orlov, Shrish Patel, James F. Smith	12,269,071	4/8/2025	Systems and Methods for Self-Cleaning Solar Panels Using an Electrodynamic Shield
  Anthony R. Lubinsky, Adrian Howansky	12,270,958	4/8/2025	Scintillating Glass Ceramics for Use in Flat Panel X-ray Detectors, Flat Panel X-ray Detectors and Imaging Systems
  Amirhossein Goldan, Andrew Labella, Wei Zhao, Anthony R. Lubinsky	12,276,764	4/15/2025	Prismatoid Light Guide
  Qingzhi Zhu	12,298,291	5/13/2025	Nitrogen Sensor Apparatus for Simultaneously Measuring Nitrate/Nitrite and Ammonium in Wastewater and Method of Operating Same
  Jingfang Ju, Andrew Fesler, Young Hwa Song, Jun Chung	12,319,913	6/3/2025	5-Halouracil-Modified microRNAs and Their Use in the Treatment of Cancer
  Iwao Ojima, Maurizio Del Poeta, Cristina Lazzarini, Krupanandan Haranahalli, Yi Sun	12,325,678	6/10/2025	Anti-Fungals Compounds Targeting the Synthesis of Fungal Sphingolipids
  Ashwanth Subamanian	12,356,877	7/8/2025	Metal-Oxide Infiltrated Organic-Inorganic Hybrid Resistive Random-Access Memory Device
  Shan Lin	12,357,080	7/15/2025	System and Method for Toothbrush Monitoring Using Magneto-Inductive Coil Sensor
  Andrew Labella, Amirhossein Goldan, Eric Petersen, Wei Zhao	12,360,262	7/15/2025	System and Method for Power-Efficient Multiplexing for High Resolution Time-of-Flight Positron Emission Tomography Modules with Intercrystal Light Sharing
  Matthew Eisaman, Jan Folkson, Joseph Andrade	12,365,592	7/22/2025	Method for Transferring Graphene from Metal Substrates
  Kenneth R. Shroyer, Luisa Escobar-Hoyos	12,366,574	7/22/2025	Keratin 17 as a Biomarker for Bladder Cancer
  Jingfang Ju, Andrew Fesler	12,371,693	7/29/2025	5-Halouracil-Modified microRNAs and Their Use in the Treatment of Cancer
  Benjamin S. Hsiao, Sunil K. Sharma, Priyanka Sharma, Ken I. Johnson	12,384,856	8/12/2025	Compositions and Methods for Removal of Negatively Charged Impurities Using Metal-Cellulose Fiber Composite
  Ya Wang, Haili Liu, Kevin Wang	12,411,046	9/9/2025	Chopped Passive Infrared Sensor Apparatus and Method for Stationary and Moving Occupant Detection
  Xianfeng Gu, Shikui Chen, Zhou Zhao, Lingfeng Gao	12,467,274	11/11/2025	Systems and Methods for Forming Multiple 3D Structures from a Circularly-Packed Network of Structural Elements
  Gerald Smaldone	12,472,314	11/18/2025	Breath Actuated Nebulizer for Ventilator Circuit
  Christopher Page, Yosman Dhar	12,478,292	11/25/2025	Devices, Systems, and Methods of Monitoring Arterial Carbon Dioxide
  Agnieszka Bialkowska, Vincent Yang	12,486,227	12/2/2025	Small Molecules for Cancer Therapy that Reduce the Expression of Transcription Factors KLF5 and EGR-1

• 2024

  Inventors	Patent No.	Issue Date	Title
  Peter Tonge, Zhuo Zhang, Peter Smith Jones, Li Liu, Hui Wang	11,857,352	1/2/2024	Positron Imaging Tomography Imaging Agent Composition and Method for Bacterial Infection
  Iwao Ojima, Maurizio Del Poeta, Cristina Lazzarini, Krupanandan Haranahalli, Yi Sun	11,858,880	1/2/2024	Anti-fungals compounds targeting the synthesis of fungal sphingolipids
  Eric Brouzes, Martin Sauzade	11,911,763	2/27/2024	Microfluidic device and methods
  Todd Griffin, Erin Healy, IV Ramakrishnan, Vikas Ashok	11,923,075	3/5/2024	System and Method Associated with Determining Physician Attribution Related to In-Patient Care Using Prediction-Based Analysis
  Dada Pisconti, Fiona Jones	11,918,570	3/5/2024	Method of Treatment for Prevention of Glucocorticoid Toxicity and/or Enhancement of Muscle Regeneration Via Neutrophil Elastase Inhibition
  Clinton Rubin	11,918,822	3/5/2024	Compositions and methods for enhancing the biological response to chemical agents and physical stimuli
  Bing Zhou, Fan Ye	11,946,761	4/2/2024	System and method associated with expedient determination of location of one or more object(s) within a bounded perimeter of 3D space based on mapping and navigation to a precise POI destination using a smart laser pointer device
  Matthew Eisaman	11,998,875	6/4/2024	System and method for electrochemical ocean alkalinity enhancement
  Esther Takeuchi, Kenneth Takeuchi, Amy Marschilok	12,002,921	6/4/2024	Solid-state silver-lithium / iodine dual-function battery formed via self-assembly
  Mengen Wang, Nusnin Akter, Yixin Xu	12,005,391	6/11/2024	Method for Trapping Noble Gas Atoms and Molecules in Oxide Nanocages
  Iwao Ojima, Vincent M. Alford, Anushree Kamath, Jian Cao, Xiaodong Ren, Nicole S. Sampson, Monaf Awwa	12,018,003	6/25/2024	Substituted pyrimidines as matrix metalloproteinase-9 hemopexin domain inhibitors
  Anthony R. Lubinsky, Wei Zhao, Adrian Howansky	12,025,757	7/2/2024	Dual-Screen Digital Radiography with Asymmetric Reflective Screens
  Fazel Khan, Imin Kao, Carlos Gabriel Helguero	12,033,324	7/9/2024	System and Method for Identifying Fractures in Digitized X-Rays
  James Scheuermann, Wei Zhao	12,041,796	7/16/2024	Fused Multi-Layer Amorphous Selenium Sensor
  Steffen Mueller, Eckard Wimmer	12,054,749	8/6/2024	Attenuation of Human Respiratory Syncytial Virus by Genome Scale Codon-Pair Deoptimization
  Anatoly Frenkel, Jiahao Huang	12,053,765	8/6/2024	Selective Carbon Dioxide Reduction Catalyzed by Single Metal Sites on Carbon Nitride Under Visible Light Irradiation
  Shan Lin	12,060,002	8/13/2024	System and Method for Tracking Human Behavior Real-Time with Single Magnetometer Sensor and Magnets
  Carol Carter, Lorna Ehrlich	12,059,413	8/13/2024	Methods of Inhibiting Viruses Using Compositions Targeting TSG101-ubiquitin Interaction
  Milutin Stanacevic, Samir Das, Petar Djuric, Akshay Athalye, Jihoon Ryoo, Yasha Karimi	12,106,173	10/1/2024	Method for Passive Wireless Channel Estimation in Radio Frequency Network Apparatus for Same
  Arie Kaufman, Konstantin Dmitriev	12,106,225	10/1/2024	System, Method, and Computer-accessible Medium for Generating Multi-class Models from Single-class Datasets
  Benjamin Hsiao, Priyanka Sharma, Sunil Sharma, Ken Johnson	12,122,687	10/22/2024	Method for Nitrogen Removal and Nitrogen Salts Recovery Using Carboxylated Cellulose Extracted by Nitro-oxidation
  Ashwanth Subramanian	12,140,865	11/12/2024	Inorganic-Infiltrated Polymer Hybrid Thin Film Resists for Advanced Lithography
  Stanislaus Wong, Lei Wang, Coray McBean, Amy C. Marschilok, Kenneth Takeuchi, Esther S. Takeuchi	12,142,754	11/12/2024	“Flower-like” LI4TI5O12-Multiwalled Carbon Nanotube Composite Structures with Performance as Highrate Anode-Materials for Li-ion Battery Applications and Methods of Synthesis Thereof
  Mohammad Hassan Arbab, Zachery Harris	12,146,790	11/19/2024	Terahertz Three-Dimensional Spectral Scanner Apparatus and Method of Using Same
  Eden Figueroa, Sonali Gera	12,184,769	12/31/2024	Quantum Network Devices, Systems, and Methods
  Fazel Khan, Imin Kao, Guangyu He	12,178,524	12/31/2024	System and Method to Conduct Bone Surgery

• 2023

  Inventors	Patent No.	Issue Date	Title
  Chuan Huang, Karl Spuhler, Mario Serrano Sosa	11,540,798	1/3/2023	Dilated Convolutional Neural Network System and Method for Positron Emission Tomography (PET) Image Denoising
  Steffen Mueller, Eckard Wimmer, Bruce Futcher, Steven Skiena,  Chen Yang	11,549,101	1/10/2023	ATTENUATED INFLUENZA VIRUSES AND VACCINES
  Jingfang Ju, Andrew Fesler	11,584,932	2/21/2023	5-HALOURACIL-MODIFIED MICRORNAS AND THEIR USE IN THE TREATMENT OF CANCER
  Benjamin Chu, Benjamin Hsiao	11,596,886	3/7/2023	Nanostructured Fibrous Membranes for Membrane Distillation
  Ramasubramanian Sekar, Junao Wang, Md Nahid Hossain, Scott Stoller	11,601,442	3/7/2023	SYSTEM AND METHOD ASSOCIATED WITH EXPEDIENT DETECTION AND RECONSTRUCTION OF CYBER EVENTS IN A COMPACT SCENARIO REPRESENTATION USING PROVENANCE TAGS AND CUSTOMIZABLE POLICY
  Fazel Khan, Michael Bielski, Jafar Khan, Imin Kao, Guangyu He	11,602,397	3/14/2023	System and method to conduct bone surgery
  Srinivas Pentyala, Sahana Pentyala	11,612,888	3/28/2023	BIOMARKER DETECTION DEVICE
  Avraham Dilmanian, Mark Schweitzer, Jameson Baker, Renee Cattell	11,628,312	4/18/2023	SYSTEM AND METHOD FOR DUAL-USE COMPUTED TOMOGRAPHY FOR IMAGING AND RADIATION THERAPY
  Amirhossein Goldan, Wei Zhao	11,710,798	7/25/2023	Selenium Photomultiplier and Method for Fabrication Thereof
  Vladimir Samuilov, Vyacheslav Solovyov, Zemfira Abutalibova	11,721,494	8/8/2023	Multi-Cell Multi-Layer High Voltage Supercapacitor Apparatus Including Graphene Electrodes
  Shan Lin	11,719,458	8/8/2023	HVAC Control Fine-Grained Occupancy Pattern Estimation
  Ming-Yu Ngai,  Katarzyna N. Hojczyk	11,724,982	8/15/2023	Trifluoromethoxylation of Arenes via Intramolecular Trifluoromethoxy Group Migration
  Iwao Ojima, Dale Deutsch, Martin Kaczocha, Kongzhen Hu, Simon Tong, Matthew Elmes, Yan Su	11,739,047	8/29/2023	Alpha-truxillic acid derivatives and pharmaceutical compositions thereof
  Joel Haskin Saltz, Tahsin Kurc, Yi Gao, Wei Zhu, Si Wen, Tianhao Zhao, Sampurna Shrestha	11,748,877	9/5/2023	SYSTEM AND METHOD ASSOCIATED WITH PREDICTING SEGMENTATION QUALITY OF OBJECTS IN ANALYSIS OF COPIOUS IMAGE DATA
  Ming-Yu Ngai, Weijia Zheng, Johnny Lee	11,760,701	9/19/2023	Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same
  Kedar Kirane, Daniel Deland,  Zongyan Zhang	11,768,193	9/26/2023	SYSTEM AND METHOD FOR CHARACTERIZING THE EQUIBIAXIAL COMPRESSIVE STRENGTH OF 2D WOVEN COMPOSITES
  Eden Figueroa, Mehdi Namazi, Mael Flament, Sonali Gera	11,784,806	10/10/2023	QUANTUM NETWORK DEVICES, SYSTEMS, AND METHODS
  Amirhossein Goldan, Andrew Labella, Wei Zhao,  Anthony R. Lubinsky	11,789,167	10/17/2023	HIGH RESOLUTION DEPTH-ENCODING PET DETECTOR WITH PRISMATOID LIGHT GUIDE ARRAY
  Anthony Lubinsky, Adrian Howansky, Wei Zhao	11,802,979	10/31/2023	Flat panel x-ray imager with scintillating glass substrate
  Emre Salman,  Milutin Stanacevic,  Yasha Karimi,  Tutu Wan, Yuanfei Huang	11,838,402	12/5/2023	ULTRA LOW POWER CORE FOR LIGHTWEIGHT ENCRYPTION
  Benjamin Lawler,  Mozhgan Rahimi Boldaji,  Brian Gainey	11,834,983	12/5/2023	Method for control of advanced combustion through split direct injection of high heat of vaporization fuel or water fuel mixtures
  Amirhossein Goldan, Andrew Labella, Wei Zhao, Anthony Lubinsky	11,841,470	12/12/2023	Prismatoid Light Guide
  Frank M. Russo	11,851,356	12/26/2023	Bioreactor system and method for nitrification and denitrification
  Arie Kaufman, Saeed Boorboor	11,854,281	12/26/2023	System, method, and computer-accessible medium for processing brain images and extracting neuronal structures